I have a problem with my camere. When I shoot 800 or 1600 ISO,there are big grading.It started happening recently, and I dont know what is this and Why is happening...
I have my camera two years

You mean there is more grain now than when you used to shoot at 1600 when the camera was new? The higher the ISO the more grain you will get, But there is a trade off in the settings of the camera as well. You can ask for more sharpening but that will cost more grain or you can ask for more noise reduction which gives you less grain but the picture is "fuzzier",

@yellodog I know but now is not grain its GRAIN when i Use any "iris",time, lights, objektive, . the grain is not normaly

If you are sure you haven't changed settings in your camera, and haven't started using new software to edit your RAW files (if you shoot in RAW) and you get this for all your lenses then I'm lost
But I have noticed some increase in grain sometimes when I use old "analogue" lenses. I'm only speculating but the sensor in a digital camera can reflect light back towards the lens. Modern lenses have a coating on the back lens to block the light but old ones do not since this wasn't a problem back than, so the light enters the lens from behind and bounces around causing flare which decreases contrast. My guess is that the camera tries to compensate by sharpening the image and the natural graininess at 1600 ISO is exaggerated. But then I'm only speculating. My second guess is that you live next to a radar station that is interfering with the electronics in your camera ;)

You might have pointed your lens directly at the sun or a very high-intensity light source (i.e. laser). Can you post comparison shots?