I'm still playing around with this and I have to say the challenge of having to work out how to do it in Affinity has proved very useful in finally forcing me to explore the software more than I have done. As a result I have done more with layers and effects in the last two days than the previous six months, so it has been a really good learning experience.
Having read yesterday that it is not possible to get a purely black and white image in Affinity with no greys that was my task for today. to prove that wrong. It's true there is no button to click to "Make it so" as Captain Picard would have said, but by playing with High Pass and Blend modes I was able to get a sort of minimal colour screen print effect in which I then shifted the few colours left to black or white in the HSL adjustments with the luminosity shift.
That is most of the hard work to produce the basic image in black shown below the blue one. Then it was a layers game with blue cut outs and Gaussian blur. I'll try to get it written out into some simple instructions if anyone wants to have a go in Affinity.
My criticism of this image would be too much fine detail so I will keep trying. I am seeing it as a teach yourself Affinity project.